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  • Question 1 - Concerning the sleep-wake cycle, Melatonin is secreted by which structure in the brain...

    Correct

    • Concerning the sleep-wake cycle, Melatonin is secreted by which structure in the brain following which environmental conditions?

      Your Answer: Pineal gland, darkness

      Explanation:

      Melatonin is secreted by the pineal gland located in the midline attached to the posterior roof of the third ventricle in the brain. Melatonin affects circadian rhythm in the body or the sleep wake cycle. The precursor to melatonin is serotonin and the rate limiting enzyme that converts serotonin to melatonin is low during the day time and reaches its peak during the night.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      12.4
      Seconds

  • Question 2 - Regarding CSF: ...

    Correct

    • Regarding CSF:

      Your Answer: Disruption of arachnoid villi function results in a communicating hydrocephalus

      Explanation:

      In normal adults CSF volume is around 125ml to 150ml. Turnover of the entire volume of cerebrospinal fluid is about 3 to 4 times a day. Composition of CSF is similar to that of plasma except that CSF is nearly protein-free compared with plasma and has different electrolyte levels. Blockage of the foramina causes an obstructive or non-communicating hydrocephalus. Communicating hydrocephalus or non-obstructive hydrocephalus is caused by impaired CSF reabsorption in the absence of any CSF flow obstruction.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      8.8
      Seconds

  • Question 3 - Regarding taste threshold and intensity discrimination: ...

    Correct

    • Regarding taste threshold and intensity discrimination:

      Your Answer: 30% change in concentration of substance tasted is necessary before an intensity difference can be detected

      Explanation:

      The ability of humans to differentiate differences in intensity of taste is poor. A 30% change in the concentration of the substance being tasted is required before an intensity difference is perceived.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.3
      Seconds

  • Question 4 - Regarding the innervation of the cerebral blood vessels, postganglionic sympathetic neurons have their...

    Correct

    • Regarding the innervation of the cerebral blood vessels, postganglionic sympathetic neurons have their cell bodies in the:

      Your Answer: Superior cervical ganglia

      Explanation:

      The superior cervical ganglion (SCG) is a part of autonomic system which plays a major role in maintaining homeostasis of the body. This ganglion innervates structures in the head and neck and is the largest and the most superiorly located ganglion. The SCG provides sympathetic innervation to structures within the head, including the pineal gland, the blood vessels in the cranial muscles and the brain, the choroid plexus, the eyes, the lacrimal glands, the carotid body, the salivary glands, and the thyroid gland. The postganglionic axons of the SCG innervate the internal carotid artery and form the internal carotid plexus. The internal carotid plexus carries the postganglionic axons of the SCG to the eye, lacrimal gland, mucous membranes of the mouth, nose, and pharynx, and numerous blood-vessels in the head.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.3
      Seconds

  • Question 5 - Regarding gustatory sensation: ...

    Correct

    • Regarding gustatory sensation:

      Your Answer: The sensory taste buds on the anterior two-thirds of the tongue travel to the chorda tympani branch of the facial nerve

      Explanation:

      There are three morphologically distinct types of taste buds including; circumvallate, fungiform and foliate. Circumvallate are rounded structures arranged in a v on the back of the tongue. The posterior third travels to glossopharyngeal nerve.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.4
      Seconds

  • Question 6 - Glucose transport in the brain is mediated by: ...

    Correct

    • Glucose transport in the brain is mediated by:

      Your Answer: GLUT 1

      Explanation:

      The facilitative glucose transporter mediates the transport of glucose from blood into neurons and glia in the brain. The primary isoforms in the brain are GLUT1 detected at high concentrations.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.8
      Seconds

  • Question 7 - The axons of the POST ganglionic neurons are mostly? ...

    Correct

    • The axons of the POST ganglionic neurons are mostly?

      Your Answer: C fibers

      Explanation:

      According to Erlanger- Grasser classification preganglionic fibers are B fibers whereas post ganglionic fibers are C fibers.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.6
      Seconds

  • Question 8 - The majority striatal neurons, called medium spiny neurons, utilizes which neurotransmitter? ...

    Correct

    • The majority striatal neurons, called medium spiny neurons, utilizes which neurotransmitter?

      Your Answer: GABA

      Explanation:

      Medium spiny neurons are inhibitory neurons which use GABA (gamma-aminobutyric acid) which exerts inhibitory actions. These cells represent 95% of neurones within the human striatum found in basal ganglia.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.6
      Seconds

  • Question 9 - Wernicke’s area: ...

    Correct

    • Wernicke’s area:

      Your Answer: Is concerned with comprehension of auditory and visual information

      Explanation:

      Wernicke’s area is located in the categorical hemisphere or left hemisphere in about 95% of right handed individuals and 60% of left handed individuals. It is involved in the comprehension or understanding of written and spoken language. In contrast Broca’s area is involved in production of language.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      12
      Seconds

  • Question 10 - The majority of corticospinal tract fibers decussate in the: ...

    Correct

    • The majority of corticospinal tract fibers decussate in the:

      Your Answer: Medulla

      Explanation:

      The corticospinal tract is a descending motor path way that begins in the cerebral cortex and decussates in the pyramids of the medulla.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.4
      Seconds

  • Question 11 - The layers of the neocortex from the 1st to the 6th are arranged...

    Correct

    • The layers of the neocortex from the 1st to the 6th are arranged as follows:

      Your Answer: Molecular, external granular, external pyramidal, internal granular, internal pyramidal, multiform

      Explanation:

      The layers of neocortex from outermost to innermost include: the molecular, external granular layer, external pyramidal, internal granular, internal pyramidal and multiform layer.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      16.3
      Seconds

  • Question 12 - Which enzyme is responsible for the removal of acetylcholine from the synapse? ...

    Correct

    • Which enzyme is responsible for the removal of acetylcholine from the synapse?

      Your Answer: Acetylcholinesterase

      Explanation:

      Acetylcholinesterase is the enzyme that is responsible for breaking down acetylcholine into choline and acetate. Both of these molecules are transported back to the presynaptic neuron to be synthesized again. This enzyme is attached to the collagen fibers of the basement membrane in the synaptic cleft.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      12.2
      Seconds

  • Question 13 - Cranial nerves VI, VII, VIII enter/exit the base of the brain at the:...

    Correct

    • Cranial nerves VI, VII, VIII enter/exit the base of the brain at the:

      Your Answer: Ponto-medullary junction

      Explanation:

      Cranial nerves III, IV and V exit from the pons, VI, VII, VIII exit from the pontomedullary junction and cranial nerve IX, X, XI, XII exit from the medulla.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.9
      Seconds

  • Question 14 - Which dorsal (sensory) root is responsible for umbilical area sensation? ...

    Correct

    • Which dorsal (sensory) root is responsible for umbilical area sensation?

      Your Answer: T10

      Explanation:

      The area of skin supplied by one nerve is called a dermatome. T10 supplies sensory neurons to the area of the umbilicus. C3 and C4 supply the neck and the shoulder, T4 supplies the dermatome at the level of the nipple, S3 supplies the inguinal region and L5 supplies the lateral aspect of the leg and the medical aspect of the dorsum of the feet plus the first 3 toes.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      3.1
      Seconds

  • Question 15 - Where is the M1 receptor mainly found? ...

    Correct

    • Where is the M1 receptor mainly found?

      Your Answer: Sympathetic postganglionic neurons

      Explanation:

      M1 receptors are found in the sympathetic postganglionic neurons.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      3.4
      Seconds

  • Question 16 - The following is true about the carotid arterial supply to the brain: ...

    Correct

    • The following is true about the carotid arterial supply to the brain:

      Your Answer: Following carotid occlusion, precapillary anastomoses are unable to prevent infarction

      Explanation:

      The brain has two sources of blood supply; the internal carotid arteries which are the anterior segment or the main artery that supplies the anterior portion of the brain, and the vertebral arteries which is the posterior segment which supplies the posterior portion of the brain. The internal carotid arteries branch and form two major arteries anterior and middle cerebral arteries. The right and left vertebral arteries fuse together at the level of the pons on the anterior surface of the brainstem to form the midline basilar artery. The basilar artery joins the blood supply from the internal carotids in an arterial ring at the base of the brain called the circle of Willis. The anterior and posterior communicating arteries conjoin the two major sources of cerebral vascular supply via the circle of Willis improving the chances of any region of the brain continuing to receive blood if one of the major arteries becomes occluded.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      15.4
      Seconds

  • Question 17 - The nucleus tractus solitaries is medullary nucleus that processes the following inputs except:...

    Incorrect

    • The nucleus tractus solitaries is medullary nucleus that processes the following inputs except:

      Your Answer: Taste from the posterior 1/3 of the tongue (CN IX)

      Correct Answer: Sensory input from the semi-circular canal (CN VIII)

      Explanation:

      Located in the brain stem is a series of purely sensory nuclei known as tractus solitaries. Inputs of the nucleus tractus solitaries include:Taste information from the facial nerve (anterior 2/3 of the tongue), glossopharyngeal nerve (posterior 1/3) and vagus nerve (small area on the epiglottis).Sensory information from the ear (auricular branch of the vagus nerve).Chemoreceptors and mechanoreceptors of the general visceral afferent pathway (GVA) in the carotid body via glossopharyngeal nerve, aortic bodies, and the sinoatrial node, via the vagus nerve.Chemically and mechanically sensitive neurons of the general visceral afferent pathway (GVA) with endings located in the heart, lungs, airways, gastrointestinal system, pharynx, and liver via the glossopharyngeal and vagus nerves.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      49.6
      Seconds

  • Question 18 - The brainstem reticular formation, consists of which important control system responsible for consciousness...

    Incorrect

    • The brainstem reticular formation, consists of which important control system responsible for consciousness and sleep?

      Your Answer: RAM reticular activated memory

      Correct Answer: RAS reticular activating system

      Explanation:

      The reticular formation is a set of interconnected nuclei that are located along the brainstem. Reticular activating system (RAS) is a set of connected nuclei in the brain that is responsible for regulating wakefulness and sleep wake transitions and is the most influential component in the reticular formation.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.7
      Seconds

  • Question 19 - In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?...

    Correct

    • In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?

      Your Answer: Putamen and Globus pallidus

      Explanation:

      The Basal Ganglia are composed of the following structures: Caudate, putamen, Globus pallidus, subthalamic nucleus and substantia nigra. The lentiform nucleus comprises of the putamen and the Globus pallidus.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.3
      Seconds

  • Question 20 - The thalamic main input from the cortex is via which tracts? ...

    Correct

    • The thalamic main input from the cortex is via which tracts?

      Your Answer: Thalamocortical pathway

      Explanation:

      The thalamus is connected to cerebral cortex via the thalamocortical radiation.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      2.7
      Seconds

  • Question 21 - Which one of the following nerve fibers has the fastest conduction velocity? ...

    Incorrect

    • Which one of the following nerve fibers has the fastest conduction velocity?

      Your Answer: β fiber

      Correct Answer: α fiber

      Explanation:

      α nerve fibers are characterized by being highly myelinated, which confers them with fast conduction properties. They innervate extrafusal skeletal muscle fibers, and their conduction velocity is between 80-120 m/s.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.5
      Seconds

  • Question 22 - The premotor cortex is: ...

    Incorrect

    • The premotor cortex is:

      Your Answer: Brodmann area 12

      Correct Answer: Brodmann area 6

      Explanation:

      A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:Primary Sensory 3,1,2Primary Motor 4Premotor 6Primary Visual 17Primary Auditory 41Brocas 44

    • This question is part of the following fields:

      • Medicine
      • Neurology
      1.1
      Seconds

  • Question 23 - Where is the aqueous humor normally reabsorbed? ...

    Incorrect

    • Where is the aqueous humor normally reabsorbed?

      Your Answer: Zonula

      Correct Answer: Canal of schlemm

      Explanation:

      Aqueous humor is a clear protein free fluid secreted by the ciliary body, it travels to the anterior chamber through the pupil and is absorbed through a network of trabeculae into the canal of schlemm

    • This question is part of the following fields:

      • Medicine
      • Neurology
      60.9
      Seconds

  • Question 24 - Where are the cell bodies to the preganglionic neurons located? ...

    Incorrect

    • Where are the cell bodies to the preganglionic neurons located?

      Your Answer: Intermediolateral column

      Correct Answer: Midbrain

      Explanation:

      The cell bodies of the preganglionic neurons are located in the lateral grey column of the spinal cord and in the motor nuclei of the 3rd, 7th, 9th and 10th cranial nerves. These cranial nerves take origin from the midbrain.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.3
      Seconds

  • Question 25 - Which part of the cerebellum is primarily responsible for equilibrium and eye movements?...

    Incorrect

    • Which part of the cerebellum is primarily responsible for equilibrium and eye movements?

      Your Answer: Cerebrocerebellum

      Correct Answer: Vestibulocerebellum

      Explanation:

      The vestibulocerebellum develops at the same time as the vestibular apparatus in the inner ear. Its regulates balance between agonist and antagonist muscle contractions of the spine, hips, and shoulders during rapid movements.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.1
      Seconds

  • Question 26 - The primary visual cortex is located in the: ...

    Correct

    • The primary visual cortex is located in the:

      Your Answer: Occipital lobe

      Explanation:

      The primary visual cortex is located in the occipital lobe.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.1
      Seconds

  • Question 27 - The parasympathetic function of the facial nerve is: ...

    Incorrect

    • The parasympathetic function of the facial nerve is:

      Your Answer: Stimulation of the pilo-erector apparatus to conserve heat in the facial region

      Correct Answer: Secretion of tears from lacrimal glands, secretion of saliva from the sublingual and submandibular salivary glands.

      Explanation:

      Facial nerve (Cranial Nerve VII) has both sensory and motor components so it is a mixed nerve. It carries axons of:General somatic afferent – to skin and the posterior earGeneral visceral efferent – which innervate sublingual, submandibular and lacrimal glands and the mucosa of the nasal cavity.General visceral afferent – provide sensation to soft palate and parts of the nasal cavity.Special visceral efferent – innervate muscles of facial expression and stapedius, the posterior belly of the digastric and the stylohyoid musclesSpecial visceral afferent – provide taste to the anterior two-thirds of the tongue via chorda tympani.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.5
      Seconds

  • Question 28 - Which neurotransmitter is found in the postganglionic parasympathetic synaptic cleft? ...

    Incorrect

    • Which neurotransmitter is found in the postganglionic parasympathetic synaptic cleft?

      Your Answer: Dopamine

      Correct Answer: Acetylcholine

      Explanation:

      Acetylcholine is the neurotransmitter released from the postganglionic parasympathetic neuron into the synaptic cleft and also by some postganglionic sympathetic neurons as well.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5
      Seconds

  • Question 29 - Which one of the following nerve fibers is involved in proprioception? ...

    Incorrect

    • Which one of the following nerve fibers is involved in proprioception?

      Your Answer: A δ fiber

      Correct Answer: An α fiber

      Explanation:

      Proprioception, also known as kinaesthesia, is the sense through which humans perceive their own position and movements. α nerve fibers are specifically involved in transmitting proprioception stimuli.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.8
      Seconds

  • Question 30 - What is the most abundant cell type in the central nervous system called?...

    Incorrect

    • What is the most abundant cell type in the central nervous system called?

      Your Answer: Schwann cell

      Correct Answer: Astrocyte

      Explanation:

      Astrocytes are the supporting cells of the central nervous system. There are two types; the fibrous type is found in the white matter and the protoplasmic type in the grey matter. They are the most abundant cell type in the CNS.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      48.5
      Seconds

  • Question 31 - Which of the following do not pass through the cavernous sinus? ...

    Incorrect

    • Which of the following do not pass through the cavernous sinus?

      Your Answer: CN 5

      Correct Answer: CN 2

      Explanation:

      Oculomotor nerve (N3), trochlear nerve (N4), ophthalmic and mandibular divisions of the trigeminal nerve (N5) pass along its lateral border. The abducent nerve (N6) passes through it along with the internal carotid artery.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      2.9
      Seconds

  • Question 32 - The thalamus is a large collection of neuronal groups within the diencephalons which...

    Incorrect

    • The thalamus is a large collection of neuronal groups within the diencephalons which participates in:

      Your Answer: Limbic functions only

      Correct Answer: Sensory, motor and limbic

      Explanation:

      The thalamus has multiple functions. It is the relay station for every sensory system (except olfactory, regulates the sleep-wake cycle and consciousness and also relays motor information.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.6
      Seconds

  • Question 33 - The hippocampus is involved in the memory of: ...

    Incorrect

    • The hippocampus is involved in the memory of:

      Your Answer: Operant conditioning

      Correct Answer: Facts

      Explanation:

      The hippocampus plays an important role in forming new memories about experienced events. Some researchers say that hippocampus plays a major role in declarative memory for example memory of facts.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.8
      Seconds

  • Question 34 - Which receptor type is associated with the inhibition of pancreatic endocrine secretion? ...

    Incorrect

    • Which receptor type is associated with the inhibition of pancreatic endocrine secretion?

      Your Answer: M2

      Correct Answer: Α2

      Explanation:

      The activation of alpha 2-adrenergic receptors in pancreatic beta-cells works by inhibiting the secretion of insulin.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      226.4
      Seconds

  • Question 35 - What is found in the posterior cavity of the eye? ...

    Incorrect

    • What is found in the posterior cavity of the eye?

      Your Answer: Aqueous humor

      Correct Answer: Vitreous humor

      Explanation:

      The eye ball contains an anterior cavity and a posterior cavity. The anterior cavity once again is divided into the anterior chamber and posterior chamber. The anterior cavity is filled with aqueous humor whereas the posterior cavity contains vitreous humor.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      23.1
      Seconds

  • Question 36 - Interruption of the left optic tract will result in which visual field defect?...

    Correct

    • Interruption of the left optic tract will result in which visual field defect?

      Your Answer: Right homonymous hemianopia

      Explanation:

      Right homonymous hemianopia is due to a lesion or pressure on the left optic tract. Total blindness of the left eye is due to a complete occlusion of the left optic nerve. Bipolar hemianopia is due to a midline chiasmal lesion. Left nasal hemianopia due to a lesion involving the left perichiasmal area. Right homonymous inferior quadrantanopia is due to involvement of the lower left optic radiations.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      14.1
      Seconds

  • Question 37 - The nucleus ambiguus: ...

    Incorrect

    • The nucleus ambiguus:

      Your Answer: Provides parasympathetic control of the parotid gland

      Correct Answer: Regulates swallowing, phonation and parasympathetic supply to the heart via CN IX, X and XI

      Explanation:

      Nucleus Ambiguus is a group of large motor neurons found deep in the medullary reticular formation. It contains cell bodies of nerves that are responsible for the innervation of muscles of speech and swallowing which are located in the soft palate, pharynx and larynx. Additionally, it contains cholinergic preganglionic parasympathetic neurons of the heart via CN X, IX and XI

    • This question is part of the following fields:

      • Medicine
      • Neurology
      12.4
      Seconds

  • Question 38 - The main reason for the prolonged effect of the withdrawal reflex is: ...

    Incorrect

    • The main reason for the prolonged effect of the withdrawal reflex is:

      Your Answer: Fast efferent conduction

      Correct Answer: Multiple connections between afferent and efferent neurons

      Explanation:

      The withdrawal reflex is a spinal reflex that protects the body from harmful stimuli. Spinal reflexes are mostly monosynaptic and are mediated by a simple reflex arc. Withdrawal reflex is mediated by a polysynaptic reflex resulting in stimulation of many motor neurons in order to establish a quick and prolonged response.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.4
      Seconds

  • Question 39 - Which one of the following cells originates from a monocyte and resembles a...

    Incorrect

    • Which one of the following cells originates from a monocyte and resembles a macrophage?

      Your Answer: Schwann cell

      Correct Answer: Microglia

      Explanation:

      Microglia act as the macrophages of the central nervous system, and they contribute to innate and adaptive immune responses. Studies have shown that microglial cells recognize monocyte antigens, and there are similarities between them that demonstrate that they originate from these monocytes.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.1
      Seconds

  • Question 40 - Where are the cell bodies of preganglionic neurons located? ...

    Incorrect

    • Where are the cell bodies of preganglionic neurons located?

      Your Answer: Spinothalamic tract

      Correct Answer: Lateral column

      Explanation:

      The cell bodies of the preganglionic neurons are located in the lateral grey column of the spinal cord and in the motor nuclei of the 3rd, 7th, 9th and 10th cranial nerves.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.3
      Seconds

  • Question 41 - The pontine tegmentum as part of the midbrain, contains which cranial nerve nuclei?...

    Incorrect

    • The pontine tegmentum as part of the midbrain, contains which cranial nerve nuclei?

      Your Answer: CN 1 to 2

      Correct Answer: CN 5 to 8

      Explanation:

      The pontine tegmentum also known as dorsal pons is located within the brain stem. Several cranial nerve nuclei are located in the pontine tegmentum. The nuclei of CN V, CN VI, CN VII and CNVIII are located in the pontine tegmentum.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.2
      Seconds

  • Question 42 - The pathway responsible for the discriminative aspect of pain, is called the: ...

    Incorrect

    • The pathway responsible for the discriminative aspect of pain, is called the:

      Your Answer: Spinothalamic tractus

      Correct Answer: Neospinothalamic tract

      Explanation:

      The spinothalamic tract is an ascending or a sensory tract, responsible for transmission of pain and temperature. The neospinothalamic tract is responsible for fast pain or discriminative pain whereas the palaeospinothalamic tract is responsible for transmission of slow pain.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      8
      Seconds

  • Question 43 - The inverse stretch reflex causing muscle relaxation when excessive force is applied to...

    Incorrect

    • The inverse stretch reflex causing muscle relaxation when excessive force is applied to a muscle is mediated by which sensory organ?

      Your Answer: Muscle stretch

      Correct Answer: Golgi tendon organ

      Explanation:

      Both the muscle spindle and Golgi tendon body are proprioceptors. The Golgi tendon reflex is a normal component of the reflex arc of the peripheral nervous system. In a Golgi tendon reflex, skeletal muscle contraction causes the antagonist muscle to simultaneously lengthen and relax. This reflex is also called the inverse myotatic reflex, because it is the inverse of the stretch reflex.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      32.1
      Seconds

  • Question 44 - During which stage of sleep is muscle tone in the limbs most reduced?...

    Incorrect

    • During which stage of sleep is muscle tone in the limbs most reduced?

      Your Answer: Stage 3

      Correct Answer: REM

      Explanation:

      Rapid eye movement (REM) stage is marked by extensive physiological changes in the body, such as accelerated respiration, increased brain activity and muscle relaxation. People dream during REM sleep, perhaps as a result of excited brain activity and the paralysis of major voluntary muscles.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.1
      Seconds

  • Question 45 - The ependyma fuse with which of the following to from the choroid plexus?...

    Incorrect

    • The ependyma fuse with which of the following to from the choroid plexus?

      Your Answer: Inferior sagittal sinus

      Correct Answer: Tela choroidea

      Explanation:

      The choroid plexus produces the cerebrospinal fluid (CSF) in the ventricles of the brain. It consists of modified ependymal cells. Tela choroidea is a region of pia mater of the meninges and underlying ependyma that’s a part of the choroid plexus. It is a very thin layer of the connective tissue of pia mater that overlies and covers the ependyma.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7
      Seconds

  • Question 46 - Which receptor type is associated with uterine contracture in pregnancy? ...

    Incorrect

    • Which receptor type is associated with uterine contracture in pregnancy?

      Your Answer: Β1

      Correct Answer: Α1

      Explanation:

      Alpha-1 adrenergic receptors cause uterine contraction during pregnancy. They are linked to Gq-proteins that activate smooth muscle contraction through the IP3 signal transduction pathway.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.2
      Seconds

  • Question 47 - Increase Gamma motor neuron activity produces what effect on the muscle spindle sensitivity?...

    Incorrect

    • Increase Gamma motor neuron activity produces what effect on the muscle spindle sensitivity?

      Your Answer: No effect

      Correct Answer: Increase

      Explanation:

      The muscle spindle is supplied by both sensory and motor nerves. Sensory supply is Type Ia fibers whereas motor supply is via gamma motor neurons. These neurons also play a role in adjusting the sensitivity of muscle spindles. Increased neuron activity increases the muscle spindle sensitivity.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.9
      Seconds

  • Question 48 - The thalamic nuclei that project over wide regions of the neocortex are: ...

    Incorrect

    • The thalamic nuclei that project over wide regions of the neocortex are:

      Your Answer: Midline nuclei only

      Correct Answer: Specific relay nuclei

      Explanation:

      The thalamus is considered the relay station for sensory and motor stimuli. There are three basic types of thalamic nuclei: relay nuclei, association nuclei and non-specific nuclei. Relay nuclei receive very well defined inputs and project this signal to functionally distinct areas of the cerebral cortex. These include the nuclei that relay primary sensations and also the nuclei involved in feedback of cerebellar signals and basal gangliar output.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      12.1
      Seconds

  • Question 49 - Into how many functional units can the cerebellum be divided? ...

    Incorrect

    • Into how many functional units can the cerebellum be divided?

      Your Answer: 5

      Correct Answer: 3

      Explanation:

      The functional division of the cerebellum are the: Vestibulocerebellum (floculonodular lobe), Spinocerebellum (vermis and associated areas in the midline) and cerebrocerebellum (lateral hemispheres).

    • This question is part of the following fields:

      • Medicine
      • Neurology
      22.6
      Seconds

  • Question 50 - The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor...

    Incorrect

    • The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor named:

      Your Answer: Gustducin

      Correct Answer: mGluR4

      Explanation:

      Umami taste or savoury taste is one of the five basic tastes described as meaty or brothy. Umami taste receptors typically respond to Glutamate. Biochemical studies have identified the taste receptors responsible for the sense of umami as modified forms of mGluR4, mGluR1 and taste receptor type 1 (T1R1), all of which have been found in all regions of the tongue bearing taste buds.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      30.4
      Seconds

  • Question 51 - Choose the correct answer: The cerebrocerebellum… ...

    Incorrect

    • Choose the correct answer: The cerebrocerebellum…

      Your Answer: Receives input via the corticopontocerebellar tracts in the middle cerebellar peduncle

      Correct Answer: All options are correct

      Explanation:

      Cerebrocerebellum is comprised of two lateral regions, the cerebellar hemispheres and communicates with the cerebral cortex. It is principally responsible for controlling coordination of movement. Three fiber bundles carry the input and output of the cerebellum. There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.9
      Seconds

  • Question 52 - Where do the meningeal veins lie? ...

    Incorrect

    • Where do the meningeal veins lie?

      Your Answer: Cerebellum

      Correct Answer: Endosteal layer of the dura

      Explanation:

      Meningeal veins lie in the endosteal layer of the dura. The veins lie lateral to the arteries.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.8
      Seconds

  • Question 53 - Which of the following tracts are involved in the control of vital functions?...

    Incorrect

    • Which of the following tracts are involved in the control of vital functions?

      Your Answer: Spinocerebellar

      Correct Answer: Reticulospinal

      Explanation:

      Reticulospinal tract pass down from the reticular formation of the mid brain, pons and medulla. It descends in the lateral white column. Both sets of fibers enter the anterior grey column and may facilitate or inhibit the gamma and alpha neurons. By this means the reticulospinal tract controls voluntary and reflex activities. It also contains the descending autonomic fiber, thus providing a pathway for the hypothalamus to control the sympathetic and parasympathetic pathways.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      49.6
      Seconds

  • Question 54 - The consensual light reflex is co-ordinated mainly in the: ...

    Incorrect

    • The consensual light reflex is co-ordinated mainly in the:

      Your Answer: Ciliary nucleus

      Correct Answer: Edinger-Westphal nucleus

      Explanation:

      The consensual light reflex occurs when an individual’s right eye is shielded and light shines into the left eye, constriction of the right pupil will occur, as well as the left. This is because the afferent signal sent through one optic nerve connects to the Edinger-Westphal nucleus, whose axons run to both the right and the left oculomotor nerves.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.6
      Seconds

  • Question 55 - On which presynaptic receptor does noradrenalin act to inhibit noradrenalin secretion? ...

    Correct

    • On which presynaptic receptor does noradrenalin act to inhibit noradrenalin secretion?

      Your Answer: Α2 receptor

      Explanation:

      Adregenic receptors are A1, A2, B1, B2, B3. Out of these, the function of the A2 receptor is inhibition of transmitter release including nor adrenalin and acetylcholine of the autonomic nervous system.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.8
      Seconds

  • Question 56 - Functions of the glossopharyngeal nerve include the following except: ...

    Incorrect

    • Functions of the glossopharyngeal nerve include the following except:

      Your Answer: Transmission of sensory input from posterior 1/3 of the tongue

      Correct Answer: Proprioceptive input from muscles of the tongue and larynx

      Explanation:

      The glossopharyngeal nerve is a mixed nerve consisting of both sensory and motor fibers. It has several branches and five distinct general functions:Branchial motor- Special visceral efferent- supplies the Stylopharyngeus muscle and superior constrictor muscle.Visceral motor- general visceral efferent- provides parasympathetic innervation of the parotid gland.Visceral sensory- general visceral afferent- carries visceral sensory information from the carotid sinus and carotid body.General sensory- general somatic afferent- provides general sensory information from the inner surface of the tympanic membrane, upper pharynx and posterior one third of the tongue.Visceral afferent- special visceral afferent- provides taste sensation from the posterior one third of the tongue including the circumvallate papillae.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.6
      Seconds

  • Question 57 - Which of the following is not innervated by the parasympathetic nerve supply? ...

    Incorrect

    • Which of the following is not innervated by the parasympathetic nerve supply?

      Your Answer: AV node

      Correct Answer: Radial muscle of iris

      Explanation:

      The sphincter pupillae is supplied by the parasympathetic fibers from the Edinger Westphal nucleus of the oculomotor nerve. The dilator pupillae (radial muscle) is supplied by the postganglionic fibers of the superior cervical sympathetic ganglion. The parasympathetic nerve supply to the salivary glands originate in the parasympathetic nucleus of the facial nerve (superior salivatory nucleus) and the glossopharyngeal nerve (inferior salivatory nucleus). The parasympathetic preganglionic fibers originate in the dorsal nucleus of the vagus nerve and descend into the thorax in the vagus nerve. The fibers terminate by synapsing with postganglionic neurons in the cardiac plexuses. Postganglionic fibers terminate on the sinoatrial and atrioventricular nodes and on the coronary arteries Parasympathetic supply to the stomach is via the vagus nerve.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.2
      Seconds

  • Question 58 - The cerebellum consist of which three lobes? ...

    Incorrect

    • The cerebellum consist of which three lobes?

      Your Answer: Anterior, posterior and superior

      Correct Answer: Anterior, posterior and flocculonodular

      Explanation:

      The cerebellum consists of 3 lobes; Anterior, Posterior and Flocculonodular lobe.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      14.2
      Seconds

  • Question 59 - Which of the following runs in the upper part of the falx cerebri?...

    Correct

    • Which of the following runs in the upper part of the falx cerebri?

      Your Answer: Superior sagittal sinus

      Explanation:

      Falx cerebri is a sickle cell fold of dura between the two hemispheres. Its posterior part blends with the superior part of the tentorium cerebelli. The superior sagittal sinus runs in its upper fixed margin, the inferior sagittal sinus in the free concave margin and the straight sinus along its attachment to the tentorium cerebelli.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.2
      Seconds

  • Question 60 - Salty taste is triggered by: ...

    Incorrect

    • Salty taste is triggered by:

      Your Answer: Hyperpolarization-activated cyclic nucleotide gated cation channel

      Correct Answer: Amiloride-sensitive sodium channel

      Explanation:

      Amiloride-sensitive sodium channels also known as epithelial Na channels is a membrane bound ion channel that is selectively permeable to Na+ ions. These channels are located throughout different epithelial membranes in the body. It is found in taste receptor cells, where it plays an important role in salt taste perception. They are also located in the kidney, the lung and the colon. Hyperpolarization-activated, cyclic nucleotide-gated (HCN) voltage-gated ion channels are widely seen in the cortex, hippocampus, thalamus and brain regions that underlie the generation of both focal and generalized-onset seizures. The metabotropic glutamate receptor (mGluRs) perform a variety of functions in the central and peripheral nervous systems. They are involved in learning, memory, anxiety, and the perception of pain. Gustducin is a G protein associated with taste and gustatory system. It plays a major role in sensation of bitter, sweet and umami stimuli.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.9
      Seconds

  • Question 61 - Which one of the following neurotransmitters is considered a monoamine? ...

    Incorrect

    • Which one of the following neurotransmitters is considered a monoamine?

      Your Answer: Norepinephrine

      Correct Answer: Acetylcholine

      Explanation:

      Acetylcholine is a major neurotransmitter in the peripheral nervous system. Monoamine neurotransmitters contain only one amino group joined to an aromatic ring. Acetylcholine is produced from acetyl-CoA and choline.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      20.9
      Seconds

  • Question 62 - Efferent innervation of the muscle spindle is supplied by which type of motor...

    Incorrect

    • Efferent innervation of the muscle spindle is supplied by which type of motor neuron?

      Your Answer: Alfa – motor neuron

      Correct Answer: Gama – motor neuron

      Explanation:

      The muscle spindle is supplied by both sensory and motor nerves. Sensory supply is via Type Ia fibers whereas the motor supply is via gamma motor neurons.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      12.1
      Seconds

  • Question 63 - Which of the following receptors are found in the liver? ...

    Incorrect

    • Which of the following receptors are found in the liver?

      Your Answer: α1, α2, β1, β2

      Correct Answer: α1, β2

      Explanation:

      Liver consists of the sympathetic Alpha 1 and beta 2 receptors.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      17.5
      Seconds

  • Question 64 - In which cell would you find a Nissl body? ...

    Incorrect

    • In which cell would you find a Nissl body?

      Your Answer: Astrocyte

      Correct Answer: Bipolar neuron

      Explanation:

      Nissl bodies are the structures of protein synthesis in neurones. They are granular bodies of Rough Endoplasmic Reticulum and ribosomes. Astrocytes, Microglia, Schwann cell, oligodendrocytes are collectively known as glia or supporting cells of the nervous system.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      8.2
      Seconds

  • Question 65 - The superior orbital fissure is the site of entry/exit for which of the...

    Incorrect

    • The superior orbital fissure is the site of entry/exit for which of the following group of nerves?

      Your Answer: CN III, IV, V3, VI

      Correct Answer: CN III, IV, V1, VI

      Explanation:

      The superior and inferior divisions of oculomotor nerve (III), trochlear nerve (IV), lacrimal, frontal and nasociliary branches of ophthalmic V1 and the abducens nerve (VI)

    • This question is part of the following fields:

      • Medicine
      • Neurology
      21.5
      Seconds

  • Question 66 - An exaggerated response to a noxious stimulus is called: ...

    Incorrect

    • An exaggerated response to a noxious stimulus is called:

      Your Answer: Allodynia

      Correct Answer: Hyperalgesia

      Explanation:

      Allodynia is the sensation of pain following non-painful stimulation.

      Hyperalgesia is enhanced intensity of pain sensation.

      Causalgia is a constant burning pain resulting from peripheral nerve injury.

      Hyperesthesia is the abnormal increase in sensitivity to stimuli of sense.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      8
      Seconds

  • Question 67 - In a 60kg adult male with normal mean arterial pressure and oxygen consumption,...

    Incorrect

    • In a 60kg adult male with normal mean arterial pressure and oxygen consumption, what proportion of the cardiac output at rest goes to the brain?

      Your Answer: 20-25%

      Correct Answer: 10-15%

      Explanation:

      The rate of cerebral blood flow in the adult is typically 750 millilitres per minute, which is 10-15% of the cardiac output. On average around 13.9% of cardiac output is distributed to the brain.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.4
      Seconds

  • Question 68 - The primary auditory cortex is: ...

    Incorrect

    • The primary auditory cortex is:

      Your Answer: Brodmann area 17

      Correct Answer: Brodmann area 41

      Explanation:

      A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:Primary Sensory 3,1,2Primary Motor 4Premotor 6Primary Visual 17Primary Auditory 41Brocas 44

    • This question is part of the following fields:

      • Medicine
      • Neurology
      3.6
      Seconds

  • Question 69 - Which afferent information is carried by the dorsal column? ...

    Correct

    • Which afferent information is carried by the dorsal column?

      Your Answer: Proprioception/ discriminative touch

      Explanation:

      The posterior grey column (dorsal column) is responsible for carrying the sensation of proprioception, two-point discrimination, and vibration to the nucleus proprius, situated anterior to the substantia gelatinosa throughout the spinal cord.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.9
      Seconds

  • Question 70 - Which of the following associations is false? ...

    Correct

    • Which of the following associations is false?

      Your Answer: Mandibular nerve – foramen lacerum

      Explanation:

      – The olfactory nerves pass through the cribriform plate- The maxillary division of the trigeminal nerve passes through the foramen rotundum- The facial nerve passes through the stylomastoid foramen- The mandibular division of the trigeminal nerve pass through the foramen ovale- The glossopharyngeal nerve passes through the jugular foramen.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.6
      Seconds

  • Question 71 - Activation of the cool receptor (CMR-1), causes: ...

    Correct

    • Activation of the cool receptor (CMR-1), causes:

      Your Answer: Influx of Ca++ & Na+

      Explanation:

      Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is an ion channel which upon activation causes the influx of Na+ and Ca++ ions into the cell that leads to the depolarization and generation of an action potential.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      34.9
      Seconds

  • Question 72 - The cavernous sinus is? ...

    Correct

    • The cavernous sinus is?

      Your Answer: Lateral to the body of the sphenoid

      Explanation:

      It is a venous sinus which creates a cavity called the lateral sellar compartment bordered by the temporal bone and the sphenoid bone. There are 2 on either side. It is about 1cm wide and extends from the posterior aspect of the orbit to the petrous part of the temporal bone. They sit on either side or lateral to the sphenoid bone.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5
      Seconds

  • Question 73 - Visual pathways - Choose the true statement: ...

    Incorrect

    • Visual pathways - Choose the true statement:

      Your Answer: The parvocellular pathway carries signals for detection of movement

      Correct Answer: The lateral geniculate nucleus, magnocellular & parvocellular pathways project to the primary visual cortex

      Explanation:

      The optic chiasm is made by the decussation of optic fibers on the nasal side. The magnocellular pathway carries signals for detection of movement. The parvocellular pathway carries cells for detection of shape, size, colour and clarity. The lateral geniculate nucleus (LGN) is the relay centre in the thalamus for he visual pathway. It has layers of magnocellular cells and parvocellular cells that are interleaved with layers of koniocellular cells. The LGN is the main central connection for the optic nerve to the occipital lobe, particularly the primary visual cortex.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      3.3
      Seconds

  • Question 74 - The spinal cord receive its blood supply from the following arteries except: ...

    Correct

    • The spinal cord receive its blood supply from the following arteries except:

      Your Answer: Lateral spinal artery

      Explanation:

      The spinal cord (SC) is supplied by the single anterior spinal artery which supplies the anterior two thirds of the SC and paired posterior spinal arteries supplying the posterior one third. Anastomoses between the spinal arteries supply the lateral column. These arteries originate near the cervico-occipital junction and therefore have a smaller calibre and often discontinue. Thus, they require reinforcement by segmental/radicular arteries which are branches of the ascending cervical artery, deep cervical artery, intercostal arteries, lumbar arteries and lateral sacral arteries

    • This question is part of the following fields:

      • Medicine
      • Neurology
      2.1
      Seconds

  • Question 75 - In the olfactory pathway: Mitral cells project to five regions of the olfactory...

    Incorrect

    • In the olfactory pathway: Mitral cells project to five regions of the olfactory cortex. Which one of the following is not one of the five regions?

      Your Answer: Amygdala

      Correct Answer: Posterior olfactory nucleus

      Explanation:

      The olfactory system contains peripheral and central divisions which are connected by transduction structures. Peripheral division consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium. Olfactory neurons are receptor cells in the epithelium that detect odour molecules dissolved in the mucus and transmit information about the odour to the brain in a process called sensory transduction. Olfactory nerves and fibers transmit information about odours from the peripheral olfactory system to the central olfactory system of the brain. The main olfactory bulb transmits pulses to both mitral and tufted cells, which help determine odour concentration. These cells also note differences between highly similar odours and use that data to aid in later recognition. The cells are different with the mitral having low firing-rates and being easily inhibited by neighbouring cells, while tufted have high rates of firing and are more difficult to inhibit. The uncus houses the olfactory cortex which includes the piriform cortex, amygdala, olfactory tubercle, and para-hippocampal gyrus. Entorhinal cortex is an area of middle temporal lobe that has connection with the para-hippocampal gyrus.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      1.3
      Seconds

  • Question 76 - Which of the following is the smallest cell of the nervous system? ...

    Incorrect

    • Which of the following is the smallest cell of the nervous system?

      Your Answer:

      Correct Answer: Microglia

      Explanation:

      Microglia are the smallest of the neuroglial cells in the nervous system. They are scattered throughout the central nervous system and have phagocytic properties.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 77 - The spinothalamic tracts are particularly concerned with… ...

    Incorrect

    • The spinothalamic tracts are particularly concerned with…

      Your Answer:

      Correct Answer: Pain and temperature sensations

      Explanation:

      The spinothalamic tracts are ascending or sensory tracts, responsible for transmission of pain and temperature.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 78 - Which serotonergic receptor is associated with vomiting? ...

    Incorrect

    • Which serotonergic receptor is associated with vomiting?

      Your Answer:

      Correct Answer: 5ht3

      Explanation:

      5ht3 is a receptor strongly associated with vomiting, present in vagal afferents, the solitary tract nucleus (STN), and the area posterior. For this reason, 5ht3 antagonists are commonly used as antiemetic drugs. They include ondansetron, tropisetron, and granisetron.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 79 - An example of cholinergic autonomic neurons are: ...

    Incorrect

    • An example of cholinergic autonomic neurons are:

      Your Answer:

      Correct Answer: Sympathetic postganglionic neurons that innervate sweat glands.

      Explanation:

      All preganglionic neurons in both the sympathetic and parasympathetic nervous system secrete acetylcholine. The postganglionic neurotransmitter of the parasympathetic nervous system in all neurons is acetylcholine. Postganglionic fibers of the sympathetic nervous system mainly secrete Noradrenalin and Adrenalin but at sweat glands and erector pili muscles the postganglionic neurotransmitter is acetylcholine.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 80 - Which part of the neuron has the highest concentration of sodium channels per...

    Incorrect

    • Which part of the neuron has the highest concentration of sodium channels per square millimetre of the cell membrane?

      Your Answer:

      Correct Answer: Nodes of Ranvier

      Explanation:

      The nodes of Ranvier contain Na+/K+ ATPases, Na+/Ca2+ exchangers and a high density of Na+ channels. The estimated concentration of sodium channels in the node is of ∼1500/μm2.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Medicine (58/75) 77%
Neurology (58/75) 77%
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